2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Cytochrome P450
  5. Cytochrome P450 Isoform
  6. Cytochrome P450 Substrate

Cytochrome P450 Substrate

Cytochrome P450 Substrates (3):

Cat. No. Product Name Effect Purity
  • HY-149769
    CP-506
    		Substrate
    CP-506 (compound 26) is an anticancer compound and a substrate for nitroreductase and CYP oxidoreductases. CP-506 has anticancer activity.
  • HY-159176
    Antitumor agent-183
    		Substrate
    Antitumor agent-183 (compound 3f) has antitumor activity with metabolic stability. Antitumor agent-183 inhibits cancer cell growth, with IC50s less than 5 nM for A549, HCT116, and HS578T cells. The albumin-bound nanoparticle formulation of Antitumor agent-183 has prolonged retention in the tumor tissues.
  • HY-W342082
    11-Ketoprogesterone
    		Substrate
    11-Ketoprogesterone (11KP4) is the substrate for CYP17A1 and 11β-HSD2 that could be metabolized to 21-deoxycortisone (21dE) and 21-deoxycortisol (21dF) with glucocorticoid activity.